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SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes

BACKGROUND: Prognosis of esophageal squamous cell carcinoma (ESCC) patients is poor and the concurrent chemoradiation therapy (CCRT) provided to ESCC patients often failed due to resistance. Therefore, development of biomarkers for predicting CCRT response is immensely important. In this study, we e...

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Detalles Bibliográficos
Autores principales: Kuo, I-Ying, Huang, Yu-Lin, Lin, Chien-Yu, Lin, Chien-Hsun, Chang, Wei-Lun, Lai, Wu-Wei, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378712/
https://www.ncbi.nlm.nih.gov/pubmed/30777052
http://dx.doi.org/10.1186/s12929-019-0510-4