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CD200-CD200R1 inhibitory signaling prevents spontaneous bacterial infection and promotes resolution of neuroinflammation and recovery after stroke

BACKGROUND: Ischemic stroke results in a robust inflammatory response within the central nervous system. As the immune-inhibitory CD200-CD200 receptor 1 (CD200R1) signaling axis is a known regulator of immune homeostasis, we hypothesized that it may play a role in post-stroke immune suppression afte...

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Detalles Bibliográficos
Autores principales: Ritzel, Rodney M., Al Mamun, Abdullah, Crapser, Joshua, Verma, Rajkumar, Patel, Anita R., Knight, Brittany E., Harris, Nia, Mancini, Nickolas, Roy-O’Reilly, Meaghan, Ganesh, Bhanu Priya, Liu, Fudong, McCullough, Louise D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378746/
https://www.ncbi.nlm.nih.gov/pubmed/30777093
http://dx.doi.org/10.1186/s12974-019-1426-3