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Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke
At the blood-brain barrier (BBB), laminin-α5 is predominantly synthesized by endothelial cells and mural cells. Endothelial laminin-α5 is dispensable for BBB maintenance under homeostatic conditions but inhibits inflammatory cell extravasation in pathological conditions. Whether mural cell-derived l...
Autores principales: | Nirwane, Abhijit, Johnson, Jessica, Nguyen, Benjamin, Miner, Jeffrey H., Yao, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378751/ https://www.ncbi.nlm.nih.gov/pubmed/30777135 http://dx.doi.org/10.1186/s40478-019-0676-8 |
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