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Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model

INTRODUCTION: Filariasis, a neglected tropical helminth disease needs vaccine besides mass drug administration for its successful eradication. METHODS: An attempt was made to produce a fusion protein (P-TUFT-ALT-2) of abundant larval transcript protein-2 and Tuftsin to enhance its immunogenicity. Th...

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Bibliographic Details
Main Authors: Paul, Rajkumar, Ilamaran, Meganathan, Khatri, Vishal, Amdare, Nitin, Reddy, Maryada Venkata Rami, Kaliraj, Perumal
Format: Online Article Text
Language:English
Published: Elsevier 2019
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378782/
https://www.ncbi.nlm.nih.gov/pubmed/30847408
http://dx.doi.org/10.1016/j.parepi.2019.e00092