CRISPR-PIN: Modifying gene position in the nucleus via dCas9-mediated tethering

Spatial organization of DNA within the nucleus is important for controlling DNA replication and repair, genetic recombination, and gene expression. Here, we present CRISPR-PIN, a CRISPR/dCas9-based tool that allows control of gene Position in the Nucleus for the yeast Saccharomyces cerevisiae. This...

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Detalles Bibliográficos
Autores principales: Lin, Jyun-Liang, Ekas, Holly, Deaner, Matthew, Alper, Hal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378893/
https://www.ncbi.nlm.nih.gov/pubmed/30820479
http://dx.doi.org/10.1016/j.synbio.2019.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378893/
https://www.ncbi.nlm.nih.gov/pubmed/30820479
http://dx.doi.org/10.1016/j.synbio.2019.02.001

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