Cargando…
CRISPR-PIN: Modifying gene position in the nucleus via dCas9-mediated tethering
Spatial organization of DNA within the nucleus is important for controlling DNA replication and repair, genetic recombination, and gene expression. Here, we present CRISPR-PIN, a CRISPR/dCas9-based tool that allows control of gene Position in the Nucleus for the yeast Saccharomyces cerevisiae. This...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378893/ https://www.ncbi.nlm.nih.gov/pubmed/30820479 http://dx.doi.org/10.1016/j.synbio.2019.02.001 |