Histological and biochemical evaluation of transforming growth factor-β activation and its clinical significance in patients with chronic liver disease

Transforming growth factor-β (TGF-β) is a key driver for liver fibrogenesis. TGF-β must be activated in order to function. Plasma kallikrein (PLK) is a TGF-β activator that cleaves the latency-associated protein (LAP) between arginine(58) and lysine(59) residues and releases active TGF-β from the la...

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Detalles Bibliográficos
Autores principales: Yokoyama, Hiroshi, Masaki, Takahiro, Inoue, Ikuyo, Nakamura, Mariko, Mezaki, Yoshihiro, Saeki, Chisato, Oikawa, Tsunekazu, Saruta, Masayuki, Takahashi, Hiroyuki, Ikegami, Masahiro, Hano, Hiroshi, Ikejima, Kenichi, Kojima, Soichi, Matsuura, Tomokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378908/
https://www.ncbi.nlm.nih.gov/pubmed/30815603
http://dx.doi.org/10.1016/j.heliyon.2019.e01231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378908/
https://www.ncbi.nlm.nih.gov/pubmed/30815603
http://dx.doi.org/10.1016/j.heliyon.2019.e01231

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