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Histological and biochemical evaluation of transforming growth factor-β activation and its clinical significance in patients with chronic liver disease

Transforming growth factor-β (TGF-β) is a key driver for liver fibrogenesis. TGF-β must be activated in order to function. Plasma kallikrein (PLK) is a TGF-β activator that cleaves the latency-associated protein (LAP) between arginine(58) and lysine(59) residues and releases active TGF-β from the la...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Hiroshi, Masaki, Takahiro, Inoue, Ikuyo, Nakamura, Mariko, Mezaki, Yoshihiro, Saeki, Chisato, Oikawa, Tsunekazu, Saruta, Masayuki, Takahashi, Hiroyuki, Ikegami, Masahiro, Hano, Hiroshi, Ikejima, Kenichi, Kojima, Soichi, Matsuura, Tomokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378908/ https://www.ncbi.nlm.nih.gov/pubmed/30815603 http://dx.doi.org/10.1016/j.heliyon.2019.e01231

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