Mapping Aldehyde Dehydrogenase 1A1 Activity using an [(18)F]Substrate‐Based Approach

Aldehyde dehydrogenases (ALDHs) catalyze the oxidation of aldehydes to carboxylic acids. Elevated ALDH expression in human cancers is linked to metastases and poor overall survival. Despite ALDH being a poor prognostic factor, the non‐invasive assessment of ALDH activity in vivo has not been possibl...

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Detalles Bibliográficos
Autores principales: Pereira, Raul, Gendron, Thibault, Sanghera, Chandan, Greenwood, Hannah E., Newcombe, Joseph, McCormick, Patrick N., Sander, Kerstin, Topf, Maya, Årstad, Erik, Witney, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379060/
https://www.ncbi.nlm.nih.gov/pubmed/30521138
http://dx.doi.org/10.1002/chem.201805473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379060/
https://www.ncbi.nlm.nih.gov/pubmed/30521138
http://dx.doi.org/10.1002/chem.201805473

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