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Optimization of dosing regimens of isoniazid and rifampicin in children with tuberculosis in India

AIMS: Pharmacokinetic studies in the past have shown inadequate antituberculosis drug levels in children with the currently available dosing regimens. This study attempted to investigate the pharmacokinetics of isoniazid and rifampicin, when used in children, and to optimize their dosing regimens. M...

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Detalles Bibliográficos
Autores principales: Aruldhas, Blessed Winston, Hoglund, Richard M., Ranjalkar, Jaya, Tarning, Joel, Mathew, Sumith K., Verghese, Valsan Philip, Bose, Anuradha, Mathew, Binu Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379231/
https://www.ncbi.nlm.nih.gov/pubmed/30588647
http://dx.doi.org/10.1111/bcp.13846