Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation

The primary monocilium, or cilium, is a single antenna-like organelle that protrudes from the surface of most mammalian cell types, and serves as a signaling hub. Mutations of cilia-associated genes result in severe genetic disorders termed ciliopathies. Among these, the most common is autosomal dom...

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Detalles Bibliográficos
Autores principales: Zhang, Peishan, Kiseleva, Anna A., Korobeynikov, Vladislav, Liu, Hanqing, Einarson, Margret B., Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379280/
https://www.ncbi.nlm.nih.gov/pubmed/30809247
http://dx.doi.org/10.3389/fgene.2019.00075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379280/
https://www.ncbi.nlm.nih.gov/pubmed/30809247
http://dx.doi.org/10.3389/fgene.2019.00075

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