Brain mGluR5 in Shank3B(−/−) Mice Studied With in vivo [(18)F]FPEB PET Imaging and ex vivo Immunoblotting

Although several studies have found that metabotropic glutamate 5 receptor (mGluR5) may play an important role in autism spectrum disorders (ASD), the mechanisms remain unclear. Here, we used a Shank3 gene complete knockout mouse model (Shank3B(−/−)) to explore the change in mGluR5 in the brain. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Guohong, Wang, Mengmeng, Wang, Shuailiang, Liu, Yi, Zhao, Yan, Zhu, Yuanyuan, Zhao, Suo, Zhang, Ming, Guo, Baolin, Yao, Han, Wang, Wenting, Wang, Jing, Wu, Shengxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379301/
https://www.ncbi.nlm.nih.gov/pubmed/30809159
http://dx.doi.org/10.3389/fpsyt.2019.00038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379301/
https://www.ncbi.nlm.nih.gov/pubmed/30809159
http://dx.doi.org/10.3389/fpsyt.2019.00038

Ejemplares similares