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Cyclooxygenase (COX)-2 Inhibitors Reduce Toxoplasma gondii Infection and Upregulate the Pro-inflammatory Immune Response in Calomys callosus Rodents and Human Monocyte Cell Line

Toxoplasma gondii is able to infect a wide range of vertebrates, including humans. Studies show that cyclooxygenase-2 (COX-2) is a modulator of immune response in multiple types of infection, such as Trypanosoma cruzi. However, the role of COX-2 during T. gondii infection is still unclear. The aim o...

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Detalles Bibliográficos
Autores principales: Pereira, Ana Carolina Alcântara, Silva, Rafaela José, Franco, Priscila Silva, de Oliveira Gomes, Angelica, Souza, Guilherme, Milian, Iliana Claudia Balga, Ribeiro, Mayara, Rosini, Alessandra Monteiro, Guirelli, Pâmela Mendonça, Ramos, Eliézer Lucas Pires, Mineo, Tiago Wilson Patriarca, Mineo, José Roberto, Silva, Neide Maria, Ferro, Eloisa Amália Vieira, Barbosa, Bellisa Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379304/
https://www.ncbi.nlm.nih.gov/pubmed/30809216
http://dx.doi.org/10.3389/fmicb.2019.00225