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Germ-Free Mice Exhibit Mast Cells With Impaired Functionality and Gut Homing and Do Not Develop Food Allergy

Background: Mucosal mast cells (MC) are key players in IgE-mediated food allergy (FA). The evidence on the interaction between gut microbiota, MC and susceptibility to FA is contradictory. Objective: We tested the hypothesis that commensal bacteria are essential for MC migration to the gut and their...

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Detalles Bibliográficos
Autores principales: Schwarzer, Martin, Hermanova, Petra, Srutkova, Dagmar, Golias, Jaroslav, Hudcovic, Tomas, Zwicker, Christian, Sinkora, Marek, Akgün, Johnnie, Wiedermann, Ursula, Tuckova, Ludmila, Kozakova, Hana, Schabussova, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379318/
https://www.ncbi.nlm.nih.gov/pubmed/30809227
http://dx.doi.org/10.3389/fimmu.2019.00205