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Multifaceted Regulations of the Serotonin Transporter: Impact on Antidepressant Response

Serotonin transporter, SERT (SLC64A for solute carrier family 6, member A4), is a twelve transmembrane domain (TMDs) protein that assumes the uptake of serotonin (5-HT) through dissipation of the Na(+) gradient established by the electrogenic pump Na/K ATPase. Abnormalities in 5-HT level and signali...

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Detalles Bibliográficos
Autores principales: Baudry, Anne, Pietri, Mathea, Launay, Jean-Marie, Kellermann, Odile, Schneider, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379337/
https://www.ncbi.nlm.nih.gov/pubmed/30809118
http://dx.doi.org/10.3389/fnins.2019.00091