Bullous Pemphigoid IgG Induces Cell Dysfunction and Enhances the Motility of Epidermal Keratinocytes via Rac1/Proteasome Activation

Bullous pemphigoid (BP) is an autoimmune disease characterized by the formation of blisters, in which autoantibodies mainly target type XVII collagen (ColXVII) expressed in basal keratinocytes. BP IgG is known to induce the internalization of ColXVII from the plasma membrane of keratinocytes through...

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Detalles Bibliográficos
Autores principales: Tie, Duerna, Da, Xia, Natsuga, Ken, Yamada, Nanako, Yamamoto, Osamu, Morita, Eishin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379344/
https://www.ncbi.nlm.nih.gov/pubmed/30809225
http://dx.doi.org/10.3389/fimmu.2019.00200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379344/
https://www.ncbi.nlm.nih.gov/pubmed/30809225
http://dx.doi.org/10.3389/fimmu.2019.00200

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