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Extracellular and intracellular small-molecule galectin-3 inhibitors

Galectin-3 is a carbohydrate binding protein which has important roles in cancer and immunity. Potent galectin-3 inhibitors have been synthesized, for experimental purposes and potential clinical use. As galectin-3 is implicated in both intra- and extracellular activities, permeability of galectin-3...

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Detalles Bibliográficos
Autores principales: Stegmayr, John, Zetterberg, Fredrik, Carlsson, Michael C., Huang, Xiaoli, Sharma, Gunjan, Kahl-Knutson, Barbro, Schambye, Hans, Nilsson, Ulf J., Oredsson, Stina, Leffler, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379368/
https://www.ncbi.nlm.nih.gov/pubmed/30778105
http://dx.doi.org/10.1038/s41598-019-38497-8