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Lambda bacteriophage nanoparticles displaying GP2, a HER2/neu derived peptide, induce prophylactic and therapeutic activities against TUBO tumor model in mice

Generating a protective and long-lasting immune response is the primary goal in the expanding field of immunotherapeutic research. In current study we designed an immunogenic bacteriophage- based vaccine to induce a cytotoxic T lymphocyte activity against a mice tumor model over-expressing HER2/neu....

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Detalles Bibliográficos
Autores principales: Razazan, Atefeh, Nicastro, Jessica, Slavcev, Roderick, Barati, Nastaran, Arab, Atefeh, Mosaffa, Fatemeh, Jaafari, Mahmoud Reza, Behravan, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379380/
https://www.ncbi.nlm.nih.gov/pubmed/30778090
http://dx.doi.org/10.1038/s41598-018-38371-z