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Hydrogen Sulfide Protects Hyperhomocysteinemia-Induced Renal Damage by Modulation of Caveolin and eNOS Interaction

The accumulation of homocysteine (Hcy) during chronic kidney failure (CKD) can exert toxic effects on the glomeruli and tubulo-interstitial region. Among the potential mechanisms, the formation of highly reactive metabolite, Hcy thiolactone, is known to modify proteins by N-homocysteinylation, leadi...

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Detalles Bibliográficos
Autores principales: Pushpakumar, Sathnur, Kundu, Sourav, Sen, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379383/
https://www.ncbi.nlm.nih.gov/pubmed/30778103
http://dx.doi.org/10.1038/s41598-018-38467-6