Precise tuning of gene expression levels in mammalian cells

Precise, analogue regulation of gene expression is critical for cellular function in mammals. In contrast, widely employed experimental and therapeutic approaches such as knock-in/out strategies are more suitable for binary control of gene activity. Here we report on a method for precise control of...

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Detalles Bibliográficos
Autores principales: Michaels, Yale S., Barnkob, Mike B., Barbosa, Hector, Baeumler, Toni A., Thompson, Mary K., Andre, Violaine, Colin-York, Huw, Fritzsche, Marco, Gileadi, Uzi, Sheppard, Hilary M., Knapp, David J. H. F., Milne, Thomas A., Cerundolo, Vincenzo, Fulga, Tudor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379387/
https://www.ncbi.nlm.nih.gov/pubmed/30778069
http://dx.doi.org/10.1038/s41467-019-08777-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379387/
https://www.ncbi.nlm.nih.gov/pubmed/30778069
http://dx.doi.org/10.1038/s41467-019-08777-y

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