Identification of FDA-approved drugs targeting the Farnesoid X Receptor

The farnesoid X receptor (FXR) belongs to the nuclear receptor family and is activated by bile acids. Multiple, chemically rather diverse, FXR agonists have been developed and several of these compounds are currently tested in clinical trials for NAFLD and cholestasis. Here, we investigated possible...

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Detalles Bibliográficos
Autores principales: van de Wiel, Sandra M. W., Bijsmans, Ingrid T. G. W., van Mil, Saskia W. C., van de Graaf, Stan F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379390/
https://www.ncbi.nlm.nih.gov/pubmed/30778102
http://dx.doi.org/10.1038/s41598-019-38668-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379390/
https://www.ncbi.nlm.nih.gov/pubmed/30778102
http://dx.doi.org/10.1038/s41598-019-38668-7

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