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Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

lncRNAs make up a majority of the human transcriptome and have key regulatory functions. Here we perform unbiased de novo annotation of transcripts expressed during the human humoral immune response to find 30% of the human genome transcribed during this process, yet 58% of these transcripts manifes...

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Detalles Bibliográficos
Autores principales: Agirre, Xabier, Meydan, Cem, Jiang, Yanwen, Garate, Leire, Doane, Ashley S., Li, Zhuoning, Verma, Akanksha, Paiva, Bruno, Martín-Subero, José I., Elemento, Olivier, Mason, Christopher E., Prosper, Felipe, Melnick, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379396/
https://www.ncbi.nlm.nih.gov/pubmed/30778059
http://dx.doi.org/10.1038/s41467-019-08679-z