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Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules

Synaptic heterogeneity is widely observed but its underpinnings remain elusive. We addressed this issue using mature calyx of Held synapses whose numbers of bouton-like swellings on stalks of the nerve terminals inversely correlate with release probability (Pr). We examined presynaptic Ca(2+) curren...

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Detalles Bibliográficos
Autores principales: Fekete, Adam, Nakamura, Yukihiro, Yang, Yi-Mei, Herlitze, Stefan, Mark, Melanie D., DiGregorio, David A., Wang, Lu-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379440/
https://www.ncbi.nlm.nih.gov/pubmed/30778063
http://dx.doi.org/10.1038/s41467-019-08452-2