On-chip combined radiotherapy and chemotherapy testing on soft-tissue sarcoma spheroids to study cell death using flow cytometry and clonogenic assay

Radiotherapy (RT) and chemotherapy (CT) are the major therapeutics to treat cancer patients. Conventional in vitro 2D models are insufficient to study the combined effects of RT and CT towards optimized dose selection or drug screening. Soft-tissue sarcomas (STS) are rare cancers with profound socia...

Descripción completa

Detalles Bibliográficos
Autores principales: Patra, Bishnubrata, Lafontaine, Julie, Bavoux, Maeva, Zerouali, Karim, Glory, Audrey, Ahanj, Mohsen, Carrier, Jean-François, Gervais, Thomas, Wong, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379442/
https://www.ncbi.nlm.nih.gov/pubmed/30778138
http://dx.doi.org/10.1038/s41598-019-38666-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379442/
https://www.ncbi.nlm.nih.gov/pubmed/30778138
http://dx.doi.org/10.1038/s41598-019-38666-9

Ejemplares similares