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On-chip combined radiotherapy and chemotherapy testing on soft-tissue sarcoma spheroids to study cell death using flow cytometry and clonogenic assay
Radiotherapy (RT) and chemotherapy (CT) are the major therapeutics to treat cancer patients. Conventional in vitro 2D models are insufficient to study the combined effects of RT and CT towards optimized dose selection or drug screening. Soft-tissue sarcomas (STS) are rare cancers with profound socia...
Autores principales: | Patra, Bishnubrata, Lafontaine, Julie, Bavoux, Maeva, Zerouali, Karim, Glory, Audrey, Ahanj, Mohsen, Carrier, Jean-François, Gervais, Thomas, Wong, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379442/ https://www.ncbi.nlm.nih.gov/pubmed/30778138 http://dx.doi.org/10.1038/s41598-019-38666-9 |
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