The Benzimidazole Derivatives, B1 (N-[(1H-Benzimidazol-2-yl)Methyl]-4-Methoxyaniline) and B8 (N-{4-[(1H-Benzimidazol-2-yl)Methoxy]Phenyl}Acetamide) Attenuate Morphine-Induced Paradoxical Pain in Mice

Despite being routinely used for pain management, opioid use is limited due to adverse effects such as development of tolerance and paradoxical pain, including thermal hyperalgesia and mechanical allodynia. Evidence indicates that continued morphine administration causes increased expression of proi...

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Detalles Bibliográficos
Autores principales: Idris, Zahida, Abbas, Muzaffar, Nadeem, Humaira, Khan, Arif-ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379466/
https://www.ncbi.nlm.nih.gov/pubmed/30809119
http://dx.doi.org/10.3389/fnins.2019.00101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379466/
https://www.ncbi.nlm.nih.gov/pubmed/30809119
http://dx.doi.org/10.3389/fnins.2019.00101

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