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Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV

Follicular helper T cells (Tfh) play critical roles instructing, and initiating T-cell dependent antibody responses. The underlying mechanisms that enhance their function is therefore critical for vaccine development. Here we apply gene array analysis identifying adenosine deaminase (ADA) as a key m...

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Detalles Bibliográficos
Autores principales: Tardif, Virginie, Muir, Roshell, Cubas, Rafael, Chakhtoura, Marita, Wilkinson, Peter, Metcalf, Talibah, Herro, Rana, Haddad, Elias K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379489/
https://www.ncbi.nlm.nih.gov/pubmed/30778076
http://dx.doi.org/10.1038/s41467-019-08801-1