Cargando…
Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV
Follicular helper T cells (Tfh) play critical roles instructing, and initiating T-cell dependent antibody responses. The underlying mechanisms that enhance their function is therefore critical for vaccine development. Here we apply gene array analysis identifying adenosine deaminase (ADA) as a key m...
Autores principales: | Tardif, Virginie, Muir, Roshell, Cubas, Rafael, Chakhtoura, Marita, Wilkinson, Peter, Metcalf, Talibah, Herro, Rana, Haddad, Elias K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379489/ https://www.ncbi.nlm.nih.gov/pubmed/30778076 http://dx.doi.org/10.1038/s41467-019-08801-1 |
Ejemplares similares
-
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection
por: Muir, Roshell, et al.
Publicado: (2016) -
A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells
por: O’Connor, Margaret H., et al.
Publicado: (2021) -
Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling
por: Chakhtoura, Marita, et al.
Publicado: (2021) -
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
por: Perreau, Matthieu, et al.
Publicado: (2013) -
Role of adenosine deaminase 2 gene variants in pediatric deficiency of adenosine deaminase 2: A structural biological approach
por: Zervou, Maria I., et al.
Publicado: (2020)