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Leptin attenuates cerebral ischemic injury in rats by modulating the mitochondrial electron transport chain via the mitochondrial STAT3 pathway

BACKGROUND: According to recent studies, leptin may exert a neuroprotective function by affecting the phosphorylation of signal transducer and activator of transcription 3 (STAT3). During stress, STAT3 regulates mitochondrial oxidative stress and reduces apoptosis. OBJECTIVE: In the present study, w...

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Detalles Bibliográficos
Autores principales: Hu, Shijun, Cheng, Daobin, Peng, Dingtian, Tan, Jing, Huang, Yanlan, Chen, Chunyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379515/
https://www.ncbi.nlm.nih.gov/pubmed/30632310
http://dx.doi.org/10.1002/brb3.1200