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Environmental Toxicant Induced Epigenetic Transgenerational Inheritance of Prostate Pathology and Stromal-Epithelial Cell Epigenome and Transcriptome Alterations: Ancestral Origins of Prostate Disease

Prostate diseases include prostate cancer, which is the second most common male neoplasia, and benign prostatic hyperplasia (BPH), which affects approximately 50% of men. The incidence of prostate disease is increasing, and some of this increase may be attributable to ancestral exposure to environme...

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Detalles Bibliográficos
Autores principales: Klukovich, Rachel, Nilsson, Eric, Sadler-Riggleman, Ingrid, Beck, Daniel, Xie, Yeming, Yan, Wei, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379561/
https://www.ncbi.nlm.nih.gov/pubmed/30778168
http://dx.doi.org/10.1038/s41598-019-38741-1