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Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin

Packaging of DNA into chromatin regulates DNA accessibility and consequently all DNA-dependent processes. The nucleosome is the basic packaging unit of DNA forming arrays that are suggested, by biochemical studies, to fold hierarchically into ordered higher-order structures of chromatin. This organi...

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Detalles Bibliográficos
Autores principales: Schwartz, Uwe, Németh, Attila, Diermeier, Sarah, Exler, Josef H, Hansch, Stefan, Maldonado, Rodrigo, Heizinger, Leonhard, Merkl, Rainer, Längst, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379673/
https://www.ncbi.nlm.nih.gov/pubmed/30496478
http://dx.doi.org/10.1093/nar/gky1203