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ExtRamp: a novel algorithm for extracting the ramp sequence based on the tRNA adaptation index or relative codon adaptiveness

Different species, genes, and locations within genes use different codons to fine-tune gene expression. Within genes, the ramp sequence assists in ribosome spacing and decreases downstream collisions by incorporating slowly-translated codons at the beginning of a gene. Although previously reported a...

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Detalles Bibliográficos
Autores principales: Miller, Justin B, Brase, Logan R, Ridge, Perry G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379678/
https://www.ncbi.nlm.nih.gov/pubmed/30649455
http://dx.doi.org/10.1093/nar/gky1193