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Single-nucleotide-resolution mapping of DNA gyrase cleavage sites across the Escherichia coli genome

An important antibiotic target, DNA gyrase is an essential bacterial enzyme that introduces negative supercoils into DNA and relaxes positive supercoils accumulating in front of moving DNA and RNA polymerases. By altering the superhelical density, gyrase may regulate expression of bacterial genes. T...

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Detalles Bibliográficos
Autores principales: Sutormin, Dmitry, Rubanova, Natalia, Logacheva, Maria, Ghilarov, Dmitry, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379681/
https://www.ncbi.nlm.nih.gov/pubmed/30517674
http://dx.doi.org/10.1093/nar/gky1222