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Single-nucleotide-resolution mapping of DNA gyrase cleavage sites across the Escherichia coli genome
An important antibiotic target, DNA gyrase is an essential bacterial enzyme that introduces negative supercoils into DNA and relaxes positive supercoils accumulating in front of moving DNA and RNA polymerases. By altering the superhelical density, gyrase may regulate expression of bacterial genes. T...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379681/ https://www.ncbi.nlm.nih.gov/pubmed/30517674 http://dx.doi.org/10.1093/nar/gky1222 |
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