MiR-146a wild-type 3′ sequence identity is dispensable for proper innate immune function in vivo

The prevailing model of microRNA function is that the “seed region” (nt 2–8) is sufficient to mediate target recognition and repression. However, numerous recent studies have challenged this model, either by demonstrating extensive 3′ pairing between physically defined miRNA–mRNA pairs or by showing...

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Detalles Bibliográficos
Autores principales: Bertolet, Grant, Kongchan, Natee, Miller, Rebekah, Patel, Ravi K, Jain, Antrix, Choi, Jong Min, Saltzman, Alexander B, Christenson, Amber, Jung, Sung Yun, Malovannaya, Anna, Grimson, Andrew, Neilson, Joel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379685/
https://www.ncbi.nlm.nih.gov/pubmed/30777858
http://dx.doi.org/10.26508/lsa.201800249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379685/
https://www.ncbi.nlm.nih.gov/pubmed/30777858
http://dx.doi.org/10.26508/lsa.201800249

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