Plasmid-based gap-repair recombineered transgenes reveal a central role for introns in mutually exclusive alternative splicing in Down Syndrome Cell Adhesion Molecule exon 4

Alternative splicing is a key feature of human genes, yet studying its regulation is often complicated by large introns. The Down Syndrome Cell Adhesion Molecule (Dscam) gene from Drosophila is one of the most complex genes generating vast molecular diversity by mutually exclusive alternative splici...

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Detalles Bibliográficos
Autores principales: Haussmann, Irmgard U, Ustaoglu, Pinar, Brauer, Ulrike, Hemani, Yash, Dix, Thomas C, Soller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379703/
https://www.ncbi.nlm.nih.gov/pubmed/30541104
http://dx.doi.org/10.1093/nar/gky1254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379703/
https://www.ncbi.nlm.nih.gov/pubmed/30541104
http://dx.doi.org/10.1093/nar/gky1254

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