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Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks

The histone H3 variant CENP-A confers epigenetic identity to the centromere and plays crucial roles in the assembly and function of the kinetochore, thus ensuring proper segregation of our chromosomes. CENP-A containing nucleosomes exhibit unique structural specificities and lack the complex profile...

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Detalles Bibliográficos
Autores principales: Sharma, Abhishek Bharadwaj, Dimitrov, Stefan, Hamiche, Ali, Van Dyck, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379705/
https://www.ncbi.nlm.nih.gov/pubmed/30590707
http://dx.doi.org/10.1093/nar/gky1298