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Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks
The histone H3 variant CENP-A confers epigenetic identity to the centromere and plays crucial roles in the assembly and function of the kinetochore, thus ensuring proper segregation of our chromosomes. CENP-A containing nucleosomes exhibit unique structural specificities and lack the complex profile...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379705/ https://www.ncbi.nlm.nih.gov/pubmed/30590707 http://dx.doi.org/10.1093/nar/gky1298 |