Cargando…

How methyl–sugar interactions determine DNA structure and flexibility

The sequence dependent structure and flexibility of the DNA double helix is of key importance for gene expression and DNA packing and it can be modulated by DNA modifications. The presence of a C5′-methyl group in thymine or the frequent C5′-methylated-cytosine affects the DNA fine structure, howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Liebl, Korbinian, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379717/
https://www.ncbi.nlm.nih.gov/pubmed/30541032
http://dx.doi.org/10.1093/nar/gky1237