Genome-wide mapping of Topoisomerase I activity sites reveal its role in chromosome segregation

DNA Topoisomerase I (TopoI) in eubacteria is the principle DNA relaxase, belonging to Type 1A group. The enzyme from Mycobacterium smegmatis is essential for cell survival and distinct from other eubacteria in having several unusual characteristics. To understand genome-wide TopoI engagements in viv...

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Detalles Bibliográficos
Autores principales: Rani, Phoolwanti, Nagaraja, Valakunja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379724/
https://www.ncbi.nlm.nih.gov/pubmed/30566665
http://dx.doi.org/10.1093/nar/gky1271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379724/
https://www.ncbi.nlm.nih.gov/pubmed/30566665
http://dx.doi.org/10.1093/nar/gky1271

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