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Extracellular glucose levels in cultures of undifferentiated mouse trophoblast stem cells affect gene expression during subsequent differentiation with replicable cell line-dependent variation
Mouse trophoblast stem cells (TSCs) have been established and maintained using hyperglycemic conditions (11 mM glucose) for no apparent good reason. Because glucose metabolites are used as resources for cellular energy production, biosynthesis, and epigenetic modifications, differences in extracellu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379769/ https://www.ncbi.nlm.nih.gov/pubmed/30318498 http://dx.doi.org/10.1262/jrd.2018-083 |