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LSEC Fenestrae Are Preserved Despite Pro-inflammatory Phenotype of Liver Sinusoidal Endothelial Cells in Mice on High Fat Diet

Healthy liver sinusoidal endothelial cells (LSECs) maintain liver homeostasis, while LSEC dysfunction was suggested to coincide with defenestration. Here, we have revisited the relationship between LSEC pro-inflammatory response, defenestration, and impairment of LSEC bioenergetics in non-alcoholic...

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Detalles Bibliográficos
Autores principales: Kus, Edyta, Kaczara, Patrycja, Czyzynska-Cichon, Izabela, Szafranska, Karolina, Zapotoczny, Bartlomiej, Kij, Agnieszka, Sowinska, Agnieszka, Kotlinowski, Jerzy, Mateuszuk, Lukasz, Czarnowska, Elzbieta, Szymonski, Marek, Chlopicki, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379824/
https://www.ncbi.nlm.nih.gov/pubmed/30809151
http://dx.doi.org/10.3389/fphys.2019.00006