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Incorporation of Modified Amino Acids by Engineered Elongation Factors with Expanded Substrate Capabilities
[Image: see text] Noncanonical amino acid (ncAA) incorporation has led to significant advances in protein science and engineering. Traditionally, in vivo incorporation of ncAAs is achieved via amber codon suppression using an engineered orthogonal aminoacyl-tRNA synthetase:tRNA pair. However, as mor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379855/ https://www.ncbi.nlm.nih.gov/pubmed/30609889 http://dx.doi.org/10.1021/acssynbio.8b00305 |