Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

[Image: see text] Phospholipase A2, group XVI (PLA2G16) is a thiol hydrolase from the HRASLS family that regulates lipolysis in adipose tissue and has been identified as a host factor enabling the cellular entry of picornaviruses. Chemical tools are essential to visualize and control PLA2G16 activit...

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Detalles Bibliográficos
Autores principales: Zhou, Juan, Mock, Elliot D., Martella, Andrea, Kantae, Vasudev, Di, Xinyu, Burggraaff, Lindsey, Baggelaar, Marc P., Al-Ayed, Karol, Bakker, Alexander, Florea, Bogdan I., Grimm, Sebastian H., den Dulk, Hans, Li, Chun T., Mulder, Laura, Overkleeft, Herman S., Hankemeier, Thomas, van Westen, Gerard J. P., van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379856/
https://www.ncbi.nlm.nih.gov/pubmed/30620559
http://dx.doi.org/10.1021/acschembio.8b00969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379856/
https://www.ncbi.nlm.nih.gov/pubmed/30620559
http://dx.doi.org/10.1021/acschembio.8b00969

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