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High-throughput sequencing of small RNAs and analysis of differentially expressed microRNAs associated with high-fat diet-induced hepatic insulin resistance in mice

BACKGROUND: Hepatic insulin resistance (IR) plays a crucial role in the development of many metabolic diseases, such as type 2 diabetes. MicroRNAs (miRNAs) are involved in the pathogenesis of IR and related diseases; however, studies of miRNAs in hepatic IR are limited. METHOD: In this study, we ado...

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Detalles Bibliográficos
Autores principales: Zhao, Xue, Chen, Zhao, Zhou, Zengyuan, Li, Yuzheng, Wang, Yuanyuan, Zhou, Zihao, Lu, Huimin, Sun, Changhao, Chu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379981/
https://www.ncbi.nlm.nih.gov/pubmed/30820263
http://dx.doi.org/10.1186/s12263-019-0630-1