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Effects of glucosamine against morphine-induced antinociceptive tolerance and dependence in mice
BACKGROUND: The most important limitations of morphine in pain therapy are its tolerance and dependence. In this study, we evaluated the protective effect of glucosamine against morphine-induced tolerance and dependence in mice. METHODS: Mice received twice daily morphine (20 mg/kg, s.c.) alone, or...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380027/ https://www.ncbi.nlm.nih.gov/pubmed/30782159 http://dx.doi.org/10.1186/s12929-019-0513-1 |