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Effects of glucosamine against morphine-induced antinociceptive tolerance and dependence in mice

BACKGROUND: The most important limitations of morphine in pain therapy are its tolerance and dependence. In this study, we evaluated the protective effect of glucosamine against morphine-induced tolerance and dependence in mice. METHODS: Mice received twice daily morphine (20 mg/kg, s.c.) alone, or...

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Detalles Bibliográficos
Autores principales: Basiri, Faezeh, Rad, Abolfazl, Mahdian, Davood, Molavi, Mehdi, Amin, Bahareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380027/
https://www.ncbi.nlm.nih.gov/pubmed/30782159
http://dx.doi.org/10.1186/s12929-019-0513-1