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Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer’s disease

BACKGROUND: Aβ(1-42) peptide abnormal production is associated with the development and maintenance of neuroinflammation and oxidative stress in brains from Alzheimer disease (AD) patients. Suppression of neuroinflammation may then represent a suitable therapeutic target in AD. We evaluated the effi...

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Detalles Bibliográficos
Autores principales: Mudò, Giuseppa, Frinchi, Monica, Nuzzo, Domenico, Scaduto, Pietro, Plescia, Fulvio, Massenti, Maria F., Di Carlo, Marta, Cannizzaro, Carla, Cassata, Giovanni, Cicero, Luca, Ruscica, Maria, Belluardo, Natale, Grimaldi, Luigi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380058/
https://www.ncbi.nlm.nih.gov/pubmed/30777084
http://dx.doi.org/10.1186/s12974-019-1417-4