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Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer’s disease
BACKGROUND: Aβ(1-42) peptide abnormal production is associated with the development and maintenance of neuroinflammation and oxidative stress in brains from Alzheimer disease (AD) patients. Suppression of neuroinflammation may then represent a suitable therapeutic target in AD. We evaluated the effi...
Autores principales: | Mudò, Giuseppa, Frinchi, Monica, Nuzzo, Domenico, Scaduto, Pietro, Plescia, Fulvio, Massenti, Maria F., Di Carlo, Marta, Cannizzaro, Carla, Cassata, Giovanni, Cicero, Luca, Ruscica, Maria, Belluardo, Natale, Grimaldi, Luigi M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380058/ https://www.ncbi.nlm.nih.gov/pubmed/30777084 http://dx.doi.org/10.1186/s12974-019-1417-4 |
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