Cargando…

Hypoxia destroys the microstructure of microtubules and causes dysfunction of endothelial cells via the PI3K/Stathmin1 pathway

BACKGROUND: Endothelial cells (EC) are sensitive to changes in the microenvironment, including hypoxia and ischemia. Disruption of the microtubular network has been reported in cases of ischemia. However, the signaling pathways involved in hypoxia-induced microtubular disruption are unknown. The pur...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Huaming, Yu, Dongsheng, Yan, Xueyun, Wang, Bing, Yu, Zhiming, Song, Yu, Sheng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380067/
https://www.ncbi.nlm.nih.gov/pubmed/30820314
http://dx.doi.org/10.1186/s13578-019-0283-1