H(2)S suppresses indoleamine 2, 3-dioxygenase 1 and exhibits immunotherapeutic efficacy in murine hepatocellular carcinoma

BACKGROUND: Over-expression and over-activation of immunosuppressive enzyme indoleamine 2, 3 -dioxygenase 1 (IDO1) is a key mechanism of cancer immune escape. However, the regulation of IDO1 has not been fully studied. The relation between hydrogen sulfide (H(2)S) and IDO1 is unclear. METHODS: The i...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Dan, Li, Tianqi, Li, Yinlong, Zhang, Shengnan, Li, Weirui, Liang, Heng, Xing, Zikang, Du, Lisha, He, Jinchao, Kuang, Chunxiang, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380069/
https://www.ncbi.nlm.nih.gov/pubmed/30777103
http://dx.doi.org/10.1186/s13046-019-1083-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380069/
https://www.ncbi.nlm.nih.gov/pubmed/30777103
http://dx.doi.org/10.1186/s13046-019-1083-5

Ejemplares similares